Ergothioneine Super Antioxidant Anti-Oxidation Anti-Glycation Brightening Skin Care Cosmetic Raw Material(CAS 497-30-3)
Product Name: Ergothioneine High-Purity Super Antioxidant Anti-Glycation Brightening Active Raw Material
INCI Name: Ergothioneine
Alias: L-Ergothioneine, Super Antioxidant Factor, Anti-Glycation Anti-Aging Ingredient, High-Stability Free Radical Scavenger, Skin Brightening Protectant, Anti-Oxidation Skincare Raw Material
CAS No.: 497-30-3 (Ergothioneine)
Appearance: Colorless and transparent crystal aqueous solution or white crystalline powder, pure texture, no peculiar odor, clean and impurity-free.
Grade: Cosmetic Premium Grade
MOQ (Minimum Order Quantity): 25KG
Solubility: Fully soluble in water and conventional polar cosmetic solvents, completely compatible with all water-phase and partial oil-phase skincare systems.
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, storage temperature 5–25℃, avoid direct strong sunlight irradiation, high temperature heating and damp environment. Keep tightly sealed after opening to prevent moisture absorption and microbial contamination, avoid long-term air exposure and oxidative failure, and ensure long-term stable anti-oxidation and anti-aging efficacy of the product.
Shelf Life: 24 Months
Ergothioneine, Super Antioxidant, Anti-Glycation, Anti-Aging, Brightening Complexion, Anti-Oxidative Stress, Skin Protection, Cosmetic Whitening Anti-Aging Raw Material
Ergothioneine Super Antioxidant Anti-Oxidation Anti-Glycation Brightening Skin Care Cosmetic Raw Material(CAS 497-30-3)
Ergothioneine is known as the "golden anti-aging antioxidant" in the high-end skincare industry, which is a rare natural high-stability super antioxidant active raw material obtained by microbial fermentation and purification.
Different from traditional antioxidant ingredients such as VC and VE which are easy to oxidize and deactivate with single efficacy, this product has ultra-strong free radical scavenging capacity and unique anti-glycation efficacy, realizing the three major core advantages of high-stability anti-oxidation, targeted anti-glycation yellowing, cellular photodamage protection.
It efficiently solves the pain points of ordinary antioxidant ingredients' poor stability, short efficacy duration, single anti-aging dimension, ineffective improvement of glycation sagging and sallow dullness.
Relying on exclusive cell targeted absorption technology, it can accurately act on skin basal cells, continuously resist external oxidative damage and internal aging metabolism, fundamentally improve skin oxidative aging and glycation aging problems.
With ultra-high safety, extreme formula stability and excellent synergistic compatibility, it is the mainstream core raw material for upgrading high-end stable anti-aging, brightening and protective skincare products.


Key Benefits
• Super Free Radical Scavenging, Superior Anti-Oxidation Ability: Its antioxidant activity is far higher than ordinary VC, VE and glutathione. It can deeply scavenge superoxide anion, hydroxyl free radicals and various oxidative metabolites in the skin, block oxidative chain reaction in an all-round way, terminate persistent skin oxidation, and reverse oxidative dull and yellow skin.
• Exclusive Anti-Glycation Technology, Improve Sagging and Yellowing: Targeted inhibition of collagen glycation cross-linking reaction, reduce the production of aging glycation products (AGEs), effectively improve skin sallowness, dull yellowing and loose sagging caused by glycation aging, firm skin texture and restore transparent and bright complexion.
• Cell-Level Photodamage Protection, Enhance Skin Defense: It can form an invisible protective film on skin cells, resist UV, blue light and environmental oxidative stress damage, protect cell activity and DNA integrity, reduce photodamage aging and sensitive fragility, and improve skin natural defense ability.
• Extreme High Stability, Long-Lasting Efficacy Release: Not easy to decompose and deactivate under high temperature, strong light and acid-base conditions, solving the defect of easy failure of traditional antioxidants. It maintains stable activity in various complex formula systems, ensuring long-lasting and consistent efficacy of finished products.
• Targeted Cellular Absorption, High Utilization Rate: Relying on the specific transporter OCTN1 in human skin cells, it can be actively absorbed and retained in cells for a long time, will not be lost with skin metabolism, achieve continuous protection and anti-aging effects, and far exceed the efficacy of ordinary passive absorption antioxidants.
• Mild & Safe with Wide Compatibility, Upgrade Product Competitiveness: Natural fermentation active, zero irritation and sensitization, suitable for all skin types. It can be compounded with various anti-aging, brightening and repairing ingredients to build a full-dimensional anti-oxidation, anti-glycation and anti-photodamage anti-aging system, comprehensively improving product high-end positioning and market differentiation advantages.
Applications
• High-End Super Antioxidant Anti-Aging Series: Core functional raw material for luxury anti-aging essence and cream. It deeply resists oxidation, scavenges free radicals, and delays overall skin aging.
• Anti-Glycation Brightening & Anti-Yellowing Products: Key active ingredient for anti-glycation, sallowness improvement and transparent brightening formulas. It improves glycation sagging and dull yellow skin, and evens skin tone.
• Photodamage Protection & Repair System: Exclusive cell protection active for anti-blue light and anti-UV skincare products. It reduces light damage aging and enhances skin light resistance.
• Long-Term Stable Anti-Aging Maintenance Series: Preferred high-stability anti-aging raw material for daily anti-oxidation maintenance formulas, solving the problem of short efficacy of ordinary antioxidants.
• Post-Sun Antioxidant Repair Products: Applied in after-sun soothing and antioxidant maintenance skincare, relieve oxidative damage caused by sun exposure, and repair light-damaged skin.
• Compound High-End Anti-Aging Synergistic System: Professional high-end synergist for multi-peptide anti-aging, whitening and repair compound formulas, comprehensively upgrading product comprehensive anti-aging efficacy.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Ergothioneine | Compliant |
Appearance | Colorless Transparent Liquid / White Crystal Powder, Odorless | Compliant |
Ergothioneine Content (%) | ≥99.0 (Customizable) | 99.2 |
Loss on Drying (%) | ≤0.5 | 0.15 |
pH Value (1% Aqueous Solution) | 5.0–7.0 | 5.7 |
Heavy Metal (Pb) | ≤1ppm | 0.1ppm |
Arsenic (As) | ≤0.5ppm | Not Detected |
Mercury (Hg) | ≤0.1ppm | Not Detected |
Cadmium (Cd) | ≤0.1ppm | Not Detected |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of Ergothioneine?
A1: The standard MOQ is 25KG, support sample orders for formula testing, anti-oxidation anti-aging efficacy debugging and finished product trial production, and support customized concentration specifications for mass production.
• Q2: What is the core formula positioning of Ergothioneine?
A2: It is a high-end luxury anti-aging active raw material integrating super anti-oxidation, anti-glycation yellowing, cell photodamage protection and stable brightening. It focuses on solving skin aging problems such as oxidative dullness, glycation sagging, photodamage fragility and unstable brightening effect, and is used for high-end long-term stable anti-aging and brightening formula upgrading.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional anti-aging maintenance: 0.01%–0.1%; High-efficiency anti-oxidation brightening essence: 0.1%–0.5%; Anti-glycation anti-yellowing series: 0.2%–0.8%; Photodamage protection repair products: 0.05%–0.3%, adjustable according to product efficacy positioning and formula system.
• Q4: What is the difference between Ergothioneine and ordinary antioxidants?
A4: Ordinary antioxidants such as VC and VE are unstable, easy to oxidize and deactivate in formulas, with single anti-oxidation efficacy and no anti-glycation ability. Ergothioneine has extreme stability, will not fail easily, has dual core efficacy of anti-oxidation and anti-glycation, and can achieve cell-targeted active absorption with long-lasting protective anti-aging effect, which is far more comprehensive and stable than ordinary antioxidants.
• Q5: What raw materials is it suitable for compounding?
A5: It is highly compatible with anti-aging peptides, bifida ferment lysate, nicotinamide, VC derivatives, glutathione and plant antioxidant extracts. The compound system can form a closed-loop anti-aging system of "anti-oxidation + anti-glycation + repair + brightening + protection", significantly improving product high-end efficacy and stability.
• Q6: What are the formula usage notes?
A6: Water-phase feeding at room temperature to 60℃ is recommended; the product has ultra-high stability with no special temperature and process restrictions; suitable for weak acid and neutral formula systems to maximize active efficacy; reasonable compounding with repair and anti-aging ingredients can achieve full-dimensional anti-aging superposition effect.
• Q7: Can it provide stable supply and professional technical support?
A7: Strictly control core indicators such as monomer content, pH value and heavy metals to ensure consistent batch stability. Support long-term bulk order supply, and provide one-stop professional services including high-stability anti-aging formula optimization, efficacy upgrading, formula debugging and after-sales technical guidance.
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